RevGenetics Ultimate 6-Compound Longevity Protocol

Third-party lab tested, every batch. View the Certificates of Analysis Buying six longevity compounds separately means six checkouts, no dosing plan, and $371.75. The Ultimate 6-Compound Protocol puts all six in one monthly supply, on a staggered schedule, for $199. Six compounds covering five pathways: NAD+, sirtuin, inflammation response, senescence, and AMPK* A public Certificate of Analysis on every batch, GMP, made in the USA Save $172.75 versus buying the same six products individually *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Try the 6-Compound Protocol for 30 days, the risk is on us. Every compound is third-party tested, backed by a public Certificate of Analysis, and made in the USA, covered by our 30-day guarantee. Third-Party Tested • Public COA • Made in USA • 30-Day Guarantee Ultimate 6-Compound Longevity Protocol: Five Pathways, One Monthly Supply The Ultimate 6-Compound Longevity Protocol combines six RevGenetics formulas into one monthly supply on a staggered daily schedule, covering NAD+, sirtuin, inflammation response, senescence, and AMPK pathways.* 6 products, 1 protocol 4.8 / 5 across 155 reviews Staggered dosing plan Save $172.75 $371.75 bought separately $199 Monthly Supply | $6.63/day | 46% off Anthony Loera, Founder & CEO of RevGenetics This guide explains which six compounds are in the protocol, why they are dosed on a staggered schedule, and how the pathway coverage fits together. About Anthony: Founded RevGenetics in 2007 | 19+ years in longevity supplement formulation | Learn more Formulas reviewed by: Dr. Hector Valenzuela, Ph.D., Chief Science Officer What You Save By Taking The Protocol $172.75 Saved Every Month Purchased individually at regular price, these six products total $371.75. As the protocol they are $199, which works out to $6.63 per day for the full six-compound stack. What that includes: Advanced NMN 1000, X500 Resveratrol, MetaCurcumin 277x, Super Z Quercetin with Zinc, DiBerberine 300x, and Super Fisetin 500. How The Individual Products Are Rated Transparency note: This protocol is newly listed, so it does not have reviews of its own yet. The ratings below belong to the six individual products inside it, left by customers who bought them separately. Verified Customer Ratings For Each Included Product Product Rating Reviews MetaCurcumin 277x 4.9 / 5 46 X500 Resveratrol 4.9 / 5 44 Advanced NMN 1000 4.8 / 5 48 Super Z Quercetin + Zinc 5.0 / 5 6 Super Fisetin 500 4.5 / 5 10 DiBerberine 300x 5.0 / 5 1 All six combined 4.8 / 5 weighted average 155 reviews Ratings come from verified customer reviews on each product's own page and are accurate as of August 2026. DiBerberine 300x is the newest formula in the lineup and has a single review so far, so read that score with the sample size in mind. The Daily Protocol (Step-by-Step) How To Take All Six Compounds Morning, with a healthy fat: Take X500 Resveratrol alongside olive oil, avocado, or another fat source to support absorption. Morning, same time: Take Advanced NMN 1000 for NAD+ precursor support.* Morning, same time: Take MetaCurcumin 277x and Super Z to complete the morning core. Before your largest meal: Take DiBerberine 300x 15 to 30 minutes before a carbohydrate-heavy meal, kept separate from curcumin. Per label: Follow the Super Fisetin 500 label for senolytic dosing. It is a six-month supply, so it is not taken daily like the others. Why the stagger: Berberine and curcumin have shown minor antagonistic effects when taken together in research models. Separating DiBerberine from the morning core keeps the AMPK and sirtuin sides of the protocol from competing in the same digestive window. Morning Core vs Mealtime: The Two-Window Approach Window 1: Morning Core (4 compounds) Products: Advanced NMN 1000, X500 Resveratrol, MetaCurcumin 277x, Super Z Pathways: NAD+ production, sirtuin signaling, healthy inflammation response, senescent-cell support* Note: Take X500 with a healthy fat. Window 2: Mealtime (1 compound) Product: DiBerberine 300x Pathway: AMPK activation and metabolic support* Timing: 15 to 30 minutes before your largest carbohydrate-containing meal, away from curcumin. Separate Track: Senolytic Product: Super Fisetin 500 Pathway: Senescent-cell support* Timing: Per label. This is a six-month supply, not a daily capsule like the rest. Protocol vs Buying The Same Six Separately Product Bought Separately In The Protocol Advanced NMN 1000 $40.00 Included X500 Resveratrol $44.95 Included MetaCurcumin 277x $54.95 Included Super Z Quercetin + Zinc $33.95 Included DiBerberine 300x $47.95 Included Super Fisetin 500 $149.95 Included Total $371.75 $199.00, save $172.75 The Six Compounds and What Each One Does Advanced NMN 1000 High-purity nicotinamide mononucleotide, a direct NAD+ precursor. NAD+ levels decline with age, and NMN is the precursor most closely studied for supporting them.* X500 Micronized Trans-Resveratrol 500mg pure trans-resveratrol per capsule, micronized for absorption. Resveratrol is the classic sirtuin-pathway compound in longevity research.* MetaCurcumin 277x Liquid micelle curcumin with tetrahydrocurcuminoids. Standard curcumin barely absorbs, which is the problem this delivery system is built to solve.* Super Z Quercetin with Zinc Micelle-delivered quercetin paired with a zinc ionophore formula, for senescent-cell and immune support.* DiBerberine 300x Enteric-coated dihydroberberine, a more bioavailable berberine metabolite, for AMPK activation and metabolic support.* Super Fisetin 500 A six-month senolytic supply at a meaningful dose. Fisetin is the flavonoid most associated with senescent-cell research.* Who This Protocol Is For A Good Fit If You Already take two or three longevity compounds and want the full stack without managing separate reorders Want pathway coverage rather than a random assortment of bottles Care about absorption technology, not just milligrams on a label Want a written dosing schedule instead of guessing at timing Quality Assurance Third-party tested every batch, ISO 17025 labs Public Certificate of Analysis GMP-certified manufacturing, made in the USA Formulas reviewed by Dr. Hector Valenzuela, Ph.D. Storage and Handling Store in a cool, dry place. No refrigeration required for any compound in the protocol. Before You Start Consult a qualified healthcare provider before use, especially if you are pregnant, nursing, taking medication, managing blood sugar, taking anticoagulant or antiplatelet medication, or preparing for surgery. If you are new to these compounds: introduce them gradually rather than all at once, so you can tell how you respond to each one. Frequently Asked Questions What is included in the Ultimate 6-Compound Longevity Protocol? Six products: Advanced NMN 1000, X500 Micronized Trans-Resveratrol, MetaCurcumin 277x, Super Z Nano Quercetin with Zinc, DiBerberine 300x, and Super Fisetin 500. Does the protocol have customer reviews? The protocol is newly listed and does not have its own reviews yet. The six products inside it hold a combined 155 verified reviews averaging 4.8 out of 5, broken down by product in the ratings table above. How is this different from the 4-Compound Protocol? The 4-Compound Protocol covers resveratrol, curcumin, quercetin, and dihydroberberine. The 6-Compound version adds Advanced NMN 1000 for NAD+ support and Super Fisetin 500 for senescent-cell support, which are the two most requested additions. How much does it save compared with buying separately? At regular prices the six products total $371.75. The protocol is $199, a saving of $172.75, or about $6.63 per day for the complete stack. Why is DiBerberine taken separately from the morning stack? Berberine and curcumin have shown minor antagonistic effects when taken together in research models. Taking DiBerberine before your largest meal keeps it in a separate digestive window from MetaCurcumin, and also lines it up with the carbohydrate load it is intended to support.* Do I take all six every day? Five are daily. Super Fisetin 500 is a six-month senolytic supply and is taken per its label rather than as a daily capsule, which is why one box lasts far longer than the others. Can I still buy the compounds individually? Yes. Every compound in the protocol is sold on its own. The protocol exists for people who want the full stack in one order at a lower combined price. Scientific References Wherry S, et al. (2025). "Combinations of histone deacetylase inhibitors extend chronological lifespan in S. cerevisiae." Yeast model research on resveratrol, curcumin, quercetin, and berberine combinations. Yousefzadeh MJ, et al. (2018). "Fisetin is a senotherapeutic that extends health and lifespan." EBioMedicine. PMID: 30279143 McReynolds MR, Chellappa K, Baur JA. (2020). "Age-related NAD+ decline." Exp Gerontol. PMID: 32097708 Camacho-Pereira J, et al. (2016). "CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction." Cell Metab. PMID: 27304511 Yoshino J, Baur JA, Imai SI. (2018). "NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR." Cell Metab. PMID: 29249689 Research context: Several of the combination findings above come from S. cerevisiae, a yeast model used in cellular aging studies. Yeast results are useful for mapping pathways and are not human lifespan results. About This Product The Ultimate 6-Compound Longevity Protocol is a complete monthly supply covering five longevity pathways in one order, with a staggered dosing schedule so the compounds are not competing in the same digestive window. Author: Anthony Loera | Reviewed by: Dr. Hector Valenzuela, Ph.D. | Publisher: RevGenetics *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use if you have medical conditions, take prescription medications, are pregnant or nursing. 6 compound longevity protocol longevity supplement bundle NMN resveratrol curcumin quercetin berberine fisetin stack complete longevity stack best longevity supplement bundle NAD+ sirtuin AMPK senolytic protocol RevGenetics 6 compound protocol