STYLAGE® XL BI-FLEX® with Lidocaine

Product Specifications Active Ingredient: Hyaluronic acid (cross-linked) 26mg/g; Lidocaine 3mg/mL Regulatory Status: CE-marked (EU); practitioners should verify current US FDA status and other applicable jurisdictions independently Molecular Type: Cross-linked hyaluronic acid (IPN-Like Technology™) with lidocaine Strength: 26mg/g HA | 3mg/mL Lidocaine Dosage Form: Injectable gel. 2 × 1mL prefilled syringes + 2 × 27G ½” & 2 × 23G ¼” needles Manufacturer: Laboratories VIVACY Brand: STYLAGE® Country of Origin: France Storage Requirements: Store below 25°C; do not freeze; protect from direct sunlight Intended Use: Severe volume loss, deep facial volumization, and structural contouring. For use only by licensed aesthetic professionals with deep-plane injection experience Who Is STYLAGE® XL BI-FLEX® with Lidocaine Indicated For, and When Should Practitioners Choose It? STYLAGE® XL BI-FLEX® with Lidocaine is indicated for licensed aesthetic professionals treating significant facial volume deficits requiring deep structural support. Common treatment areas and clinical applications include: Cheeks & Temples: Deep subcutaneous volumization to correct age-related hollowing. Midface: Restoration of lost malar volume and support of overlying soft tissue. Jawline & Cheekbones: High-definition structural contouring and bone-level augmentation. Chin Projection: Supraperiosteal placement to improve anterior chin projection and symmetry. It may also be used for deep correction of nasolabial folds and marionette lines where severe underlying volume deficiency is a primary contributing factor. Patient selection should account for the condition of the patient’s skin and underlying tissue support, individual treatment objectives, facial anatomy, and practitioner experience with supraperiosteal and deep subcutaneous injection techniques. When to Choose STYLAGE® XL STYLAGE® XL BI-FLEX® with Lidocaine is generally selected when greater structural support and volumizing capacity are required than can be achieved with STYLAGE® L or STYLAGE® M. It is intended for advanced correction of significant facial volume deficits and contour deficiencies. For superficial lines, fine wrinkles, and mild-to-moderate volume restoration, lighter STYLAGE® formulations are typically more appropriate. How Does STYLAGE® XL BI-FLEX® with Lidocaine Work, and What Is the Clinical Role of Lidocaine at XL Depth? The high concentration of cross-linked hyaluronic acid (26mg/g) integrates into deep facial tissues and attracts water molecules, providing immediate volumization and long-lasting structural support to address severe volume loss and enhance facial contours at deeper anatomical levels. IPN-Like Technology™ utilizes two interlocked hyaluronic acid polymer networks to improve gel cohesivity, elasticity, and resistance to deformation, helping the filler maintain support in facial areas exposed to continuous movement and mechanical stress. Results vary depending on factors such as skin type, treatment area, lifestyle, and injection technique, with clinical outcomes typically lasting approximately 12 months or longer. The product is fully reversible through hyaluronidase administration when correction or reversal is required. The inclusion of 3mg/mL lidocaine enhances patient comfort during deep subcutaneous and supraperiosteal injections. By temporarily blocking sodium channel activity involved in pain transmission, lidocaine reduces procedural discomfort without requiring a separate anesthetic injection, improving both patient tolerability and treatment efficiency. This is a clinically meaningful advantage at the injection depths required for XL-level correction. How Is STYLAGE® XL BI-FLEX® with Lidocaine Administered, and What Are the Safety Considerations? STYLAGE® XL BI-FLEX® with Lidocaine is intended for administration at supraperiosteal or deep subcutaneous levels by qualified aesthetic professionals with experience in deep-plane injection techniques, facial anatomy, and vascular safety protocols. Lidocaine is co-formulated at 3mg/mL; supplemental local anesthesia may still be used at the practitioner’s discretion, depending on patient sensitivity and treatment complexity. Following treatment, patients should avoid excessive sun exposure and other activities that may exacerbate swelling until symptoms resolve. Because this product is designed for deep volumization, post-treatment swelling may be more pronounced and longer-lasting than that observed with superficial injectable dermal fillers; patients should be counseled accordingly before treatment. Common and Serious Side Effects The following localized injection-site reactions are generally mild, expected inflammatory responses that typically resolve spontaneously within a few days without clinical intervention: Redness and erythema Transient swelling or localized edema Tenderness and sensitivity to palpation Minor bruising or ecchymosis While uncommon, deep-plane dermal injections carry inherent anatomical risks. Practitioners must be fully trained to immediately recognize and manage the following complications using emergency protocols: Vascular Occlusion: Accidental intravascular injection leading to tissue ischemia and necrosis. Infections: Delayed-onset nodules or bacterial/biofilm introduction requiring antibiotic therapy. Visual Disturbances: Embolization leading to severe ophthalmic complications (extremely rare but requires immediate emergency referral). Patients must be thoroughly screened for hypersensitivity to hyaluronic acid or amide-type local anesthetics prior to treatment, and the manufacturer’s official Instructions for Use (IFU) should be reviewed in full before administration. What Is the Regulatory Status of STYLAGE® XL BI-FLEX® with Lidocaine? STYLAGE® XL BI-FLEX® with Lidocaine is manufactured by Laboratories VIVACY in France and is CE-marked for professional use within applicable European markets. As a medical device intended for aesthetic procedures, it should only be handled and administered by qualified healthcare professionals with appropriate training in facial anatomy and injection techniques. Access may be restricted to licensed practitioners and registered aesthetic clinics, depending on regional regulations. STYLAGE® products are CE-marked for use in the European Union; regulatory status may vary by country, and practitioners should verify current approval, importation, and distribution requirements within their jurisdiction before procurement or clinical use. Practitioners who wish to buy dermal fillers or buy STYLAGE® may contact Medical Spa Rx’s professional support team for sourcing information and documentation support. Practitioners evaluating wholesale options for STYLAGE® XL BI-FLEX® should confirm that suppliers comply with applicable storage, transport, and regulatory standards. When buying online, practitioners should ensure that products originate from legitimate, properly authorized sources. Regulatory information is current as of mid-2026; local verification is essential before purchase or treatment. For sourcing guidance, contact Medical Spa Rx’s professional support team.