STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine

Product Specifications Active Ingredient: Hyaluronic acid (cross-linked) 20mg/mL; Lidocaine 0.3%; Mannitol 0.3% Regulatory Status: CE-marked (EU); practitioners should verify current US FDA status and other applicable jurisdictions independently Molecular Type: Cross-linked hyaluronic acid (IPN-Like Technology™) with lidocaine Strength: 20mg/mL HA | 0.3% Lidocaine | 0.3% Mannitol Dosage Form: Injectable gel — 1 × 1mL prefilled syringe + 2 × 30G ½ needles Manufacturer: Laboratories VIVACY Brand: STYLAGE® Country of Origin: France Storage Requirements: Store below 25°C; do not freeze; protect from direct sunlight Intended Use: Lip augmentation and perioral volume restoration — for licensed aesthetic professionals Who Is STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine Indicated For? STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine is intended for aesthetic medicine professionals seeking a product specifically developed for lip enhancement procedures. Unlike many injectable dermal fillers adapted from broader facial indications, this formulation was designed to address the unique structural and dynamic characteristics of the lip treatment area. Lip Augmentation and Volume Restoration The primary indication for STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine injection is lip augmentation. The formulation helps restore volume, improve lip projection, and enhance overall lip shape while maintaining natural movement and expression. Patients experiencing age-related volume loss or naturally thin lips may benefit from the product’s higher hyaluronic acid concentration. The 20mg/mL HA content supports more pronounced augmentation than lower-concentration lip filler formulations. Perioral Treatment Applications In addition to lip volume enhancement, the product may be used in selected perioral treatment areas, including vermillion border definition, philtrum column enhancement, perioral rhytid correction, and lip contour refinement. Patient Selection Considerations Successful outcomes depend on a careful clinical assessment. Practitioners should evaluate the patient’s anatomy, volume loss, skin quality, and medical history. Many injectors choose STYLAGE® due to its specific lip-focused characteristics: Lips Plus Concentration: A 20 mg/mL cross-linked hyaluronic acid formulation built for pronounced volume. IPN-Like Technology™: Interconnected polymer networks that resist mechanical breakdown from lip movement. Bi-FLEX® Delivery: Next-generation ergonomic syringes designed for maximum precision and injection control. Integrated Lidocaine: Formulated with 0.3% lidocaine to ensure patient comfort during treatment. How Does STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine Work? Following injection, the cross-linked hyaluronic acid (HA) gel integrates smoothly into the lip tissue. It delivers immediate volumization, sharp contouring, and natural-looking aesthetic outcomes through three core mechanisms: Dynamic Adaptation (IPN-Like Technology™): The gel utilizes two interconnected HA polymer networks. This interpenetrating network enhances cohesivity and structural integrity, allowing the filler to withstand constant mechanical stress from speaking or eating without migrating. Oxidative Protection (Mannitol Integration): Formulated with the powerful antioxidant mannitol, the gel actively sweeps up free radicals in the highly vascularized lip tissue. This safeguards the HA chains against immediate post-injection oxidative stress, significantly extending the lifespan of the correction. Hydrophilic Volumization: The cross-linked HA molecules bind water tightly within the tissue, providing deep hydration that maintains a soft, natural feel while sustaining lip projection over time. For patient comfort, the formulation integrates 0.3% lidocaine to minimize discomfort in the highly sensitive perioral region. As with all standard HA fillers, the effect is completely reversible with hyaluronidase if adjustments are required. What Is STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine? STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine is a dedicated lip filler manufactured by Laboratories VIVACY in France, developed specifically for professional lip augmentation procedures and incorporating the company’s proprietary IPN-Like Technology™. The LIPS PLUS designation reflects the product’s elevated hyaluronic acid concentration of 20mg/mL. This differentiates it from lower-concentration lip fillers intended for more subtle enhancement and makes it particularly suitable for patients requiring noticeable correction of lip volume loss. The product package includes one prefilled 1mL syringe and two 30G ½ needles to support precise product placement during treatment. Unlike STYLAGE® M and STYLAGE® L formulations, STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine does not contain mannitol. The formulation focuses specifically on achieving optimal lip volume, contour definition, and handling characteristics for the lip treatment area. How Is STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine Administered, and What Are the Safety Considerations?  STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine should only be administered by qualified aesthetic professionals familiar with lip anatomy, vascular safety protocols, and complication management. Injection may be performed in the lip body, vermillion border, or philtrum columns, with depth and technique determined by practitioner preference, patient anatomy, and desired augmentation outcome. The product contains 0.3% lidocaine; practitioners may apply additional topical anesthetics as appropriate.  Following treatment, patients should avoid excessive sun exposure and unnecessary manipulation of the treated area until redness and swelling resolve. Bruising at the injection site may occur and typically resolves within a few days.  Side Effects & Safety Profile While STYLAGE® Lips Plus Bi-FLEX® is generally well-tolerated, practitioners must distinguish between typical post-injection reactions and rare, severe medical complications: Common Reactions: Minor side effects are temporary, localized to the perioral area, and typically resolve spontaneously within a few days. These include localized swelling, redness, tenderness, and bruising at the injection site. Serious Adverse Events: Though rare, severe complications require immediate recognition and intervention. Accidental intravascular injection can lead to vascular occlusion, skin necrosis, or visual disturbances. Injectors must be trained in emergency management and maintain immediate access to hyaluronidase. Contraindications: Treatment should not proceed if the patient has an active infection at the injection site or a known hypersensitivity to hyaluronic acid or amide-type local anesthetics, such as lidocaine. Always consult the manufacturer’s official Instructions for Use (IFU) for a full breakdown of safety parameters, warnings, and absolute contraindications before proceeding with treatment. What Is the Regulatory Status of STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine? STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine is manufactured in France by Laboratories VIVACY and is CE-marked for professional aesthetic use within applicable European markets. The product is restricted to licensed medical professionals and registered aesthetic clinics. Regulatory status may vary by country and jurisdiction, and practitioners should independently verify all local requirements before procurement or clinical use. Practitioners who wish to buy dermal fillers or buy STYLAGE® may contact Medical Spa Rx’s professional support team for sourcing information and documentation support. Practitioners evaluating buy STYLAGE® LIPS PLUS BI-FLEX® wholesale options should confirm that suppliers comply with applicable storage, transport, and regulatory standards. When buying online, practitioners should ensure that products originate from legitimate, properly authorized sources. Regulatory information is current as of mid 2026. For sourcing guidance, contact Medical Spa Rx’s professional support team.