NeuroRegenex, 60 Tablets

NeuroRegenex is a unique herbal formulation containing curcumin extract, Boswellia, Bupleurum root, and Gotu Kola extract to provide rejuvenating brain support.* The herbs in NeuroRegenex work to: Tonify the brain and support healthy mental clarity, cognition and memory function, as used traditionally in Ayurveda* Rejuvenate and support the body’s natural ability to adapt to temporary stress, as used traditionally in Ayurveda* Support a healthy inflammatory response* Support systemic antioxidant activity* MediHerb® NeuroRegenex offers a specialized extract of Turmeric with FenuMAT™ technology for enhanced bioavailability of curcumin. It also contains Boswellia with FenuMAT™, Bupleurum root, and Gotu Kola extract which is standardized for triterpenes. Advantages of MediHerb® NeuroRegenex Optimal Strength Ingredients Each tablet is standardized to contain 67 mg curcuminoids (providing 55 mg of curcumin) and 20 mg of Gotu Kola triterpenes to ensure optimal strength and quality. Enhanced Bioavailability with FenuMAT™ Technology FenuMAT™ utilizes Fenugreek galactomannans: a natural prebiotic fiber that enhances the absorption of active constituents such as curcumin. Formulated for Brain Health Through supporting the body's healthy stress response and tonifying the brain, it supports mental clarity, cognition and memory function.* How MediHerb® NeuroRegenex Supports Your Health MediHerb® NeuroRegenex is a unique formulation that provides a specialized, bioavailable form of curcumin from Turmeric.  The extent to which a substance is absorbed and therefore available to the body is called bioavailability. Unformulated Turmeric is known to have low bioavailability.1 However, this advanced extract of Turmeric harnesses FenuMAT™ technology to enhance its bioavailability. FenuMAT™ utilizes Fenugreek galactomannans: a natural prebiotic fiber that forms a self-emulsifying protective hydrogel that protects Turmeric’s active phytochemicals (known as curcuminoids and curcumin) from degradation in the upper gastrointestinal tract. FenuMAT™ also increases attachment to the gastric mucosa, allowing slow release into the epithelium, promoting direct absorption into circulation and the lymphatic system.*2 Curcumin with FenuMAT™ technology has demonstrated 45-times greater systemic bioavailability of free curcumin compared to unformulated curcumin.*3 Supports the Body’s Antioxidant and Natural Inflammatory Response Processes* Turmeric has been used as a food and in herbal preparations for thousands of years. It has a long list of traditional health benefits across several cultural healthcare systems, including Ayurveda, traditional Chinese practice, and traditional Islamic herbal practice. Modern science supports this long tradition, with Turmeric and its key active phytochemical curcumin, being well studied in the scientific literature.4  It is well known to support a healthy inflammatory response,*5  by supporting the body’s management of immunological mediators such as tumor necrosis factor alpha (TNF-α),6 interleukin 6, 7 nitric oxide and nuclear factor kappa-light-chain-enhancer of activated B cell (NFκB).8  It is also a well-regarded antioxidant.*6 Contains Boswellia Boswellia oleoresin is one of the oldest and most highly valued herbs in the Ayurvedic and Unani traditions. The resin contains various terpenes, the most important of which are the pentacyclic triterpenes collectively known as boswellic acids.  Tonifies the Brain* In Ayurveda, Gotu Kola is a key herb used for the revitalization of the nerves and brain. It is considered a Medhya-Rasayana herb, or rejuvenating brain tonic. It is commonly used to support healthy cognition and memory function.*9  Supports the Body’s Natural Ability to Respond to Stress* Gotu Kola is a key Rasayana herb in Ayurveda. Rasayanas are said to act as adaptogens - substances which support the body’s resistance to everyday mild stressors and support normal physiological functioning. Rasayanas are also said to enrich the tissues, rejuvenate body and mind, promote healthy aging, vitality, vigor, and intellect.*9 Contains Bupleurum Bupleurum is an important remedy in traditional Chinese and Kampo herbal practice. In this tradition, 3-9 g per day of dried root preparations are used to spread Liver Qi, which helps to soothe occasional emotional distress and irritability associated with Liver Qi stagnation.10 Bupleurum naturally contains triterpene saponins, including saikosaponins.*11 Frequently Asked Questions Who may benefit from taking MediHerb® NeuroRegenex? Those who wish for support to maintain healthy brain function Those who desire support to maintain healthy mental clarity, cognition and memory Those facing everyday life challenges, who are seeking a rejuvenating tonic to support a healthy stress response Those who may benefit from herbs that support the body’s natural antioxidant and inflammatory responses, to maintain well-being. Why are antioxidants important for the maintenance of normal brain health and cognitive function?* The brain has a high metabolic rate, utilizing more than 20% of the body’s oxygen and energy. This metabolic activity naturally produces reactive oxygen species within the brain - a normal process in healthy individuals. Antioxidants can aid in the maintenance of brain health by acting as free radical scavengers, mopping up reactive oxygen species and supporting the maintenance of neuronal health.*12 A systematic review involving 31 human clinical trials found that consumption of plant antioxidants can help maintain healthy cognitive function in young, adult, and elderly people.*13  What is FenuMAT™ technology and how is this different than formulations with black pepper? FenuMAT™ technology enhances the bioavailability of fat-soluble herbs at low doses. Non-digestible fiber from fenugreek forms a protective hydrogel to protect these phytochemicals through the digestive process. It also allows slow release directly into circulation and the lymphatic system. The actions of black pepper extracts are different. They change the dynamics of the gastrointestinal membrane, which can affect the bioavailability of other nutrients or medications taken concurrently.14 References:    Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of Curcumin: Problems and Promises. Mol Pharmaceutics. 2007 Dec 1;4(6):807-18. DOI:10.1021/mp700113r Arkay Natural Ingredients. Technology [Internet]. Kerala: Arkay Natural Ingredients; 2021 [cited 2022 Feb 09]. Available from: https://www. curqfen.net/technology/# Kumar D, Jacob D, Subash PS, Maliakkal A, Johannah NM, Kuttan R, et al. Enhanced Bioavailability and relative distribution of free (unconjugated) curcuminoids following the oral administration of a food-grade formulation with fenugreek dietary fi bre: a randomised double-blind crossover study. J Funct Foods. 2016 Apr 1;22:578-87. Akaberi M, Sahebkar A, Emami SA. Turmeric and curcumin: from traditional to modern medicine. Studies on Biomarkers and New Targets in Aging Research in Iran: Focus on Turmeric and Curcumin. Adv Exp Med Biol. 2021;1291:15-39. Health Canada, ‘CURCUMIN’, Aug 28, 2018. Accessed 20/07/2020 from http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=curcumin.curcumine&lang=eng Sahebkar A, Cicero AFG, Simental-Mendía LE, Aggarwal BB, Gupta SC. Curcumin A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2016;107:234-242. doi:10.1016/j.phrs.2016.03.026 Meta-analysis / PS Derosa G, Maffi oli P, Simental-Mendía LE, Bo S, Sahebkar A. Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2016;111:394-404. doi:10.1016/j. phrs.2016.07.004 Yu Y, Shen Q, Lai Y, Park SY, Ou X, Lin D, Jin M, et al. Front Pharmacol. 2018 Apr 20;9:386. https://doi.org/10.3389/fphar.2018.00386 Chaudhry B. Key Rasayana Plants of Ayurveda. EWIJST. 2021 Apr 10;16:53-73. Chen JK, Chen TT. Chinese medical herbology and pharmacology. Art of Medicine Press, USA, 2012. World Health Organization. WHO monographs on selected medicinal plants. World Health Organization, Volume 1, Geneva, 1999, pp. 67-76. Gomez-Pinilla F, Nguyen TTJ. Nutr. Neurosci. 2012 May;15(3):127-33. DOI:10.1179/1476830511Y.0000000035 Baroni L, Sarni AR, Zuliani C. Plant Foods Rich in Antioxidants and Human Cognition: A systematic Review. Antioxidants. 2021 Apr 30;10(5):714. DOI:10.3390/antiox10050714 Imran M, Samal M, Qadir A, Ali A, Mir SR. A critical review on the extraction and pharmacotherapeutic activity of piperine. Polim Med. 2022 Jan-Jun;52(1):31-36. doi: 10.17219/pim/145512. PMID: 35196422. Suggested Use: 2 tablets, 3 times daily, or as directed Cautions: Contraindicated in known allergy to Gotu Kola. Not to be used in pregnancy and lactation unless otherwise directed by a qualified healthcare professional. For other contraindications and cautions consult your healthcare professional. Keep out of reach of children. Store in a cool, dry place out of direct sunlight. Nutrients & Ingredients Each Serving Size (2 Tablets) contains: Calories 5, Calcium 142 mg, Gotu Kola leaf 10:1 extract 200 mg (from Centella asiatica leaf 2 g, Containing triterpenes 40 mg), Turmeric rhizome 55:1 extract 156 mg (from Curcuma longa rhizome 8.6 g, Containing curcuminoids 135 mg, Equivalent to curcumin 110 mg), Boswellia oleo-gum-resin 23:1 extract 88 mg (from Boswellia serrata oleo-gum-resin 2 g), Bupleurum root 6:1 extract 166.7 mg (from Bupleurum falcatum root 1 g). Other Ingredients: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, fenugreek seed fiber (FenuMATTM), croscarmellose sodium, silicon dioxide, sunflower lecithin, magnesium stearate, sodium starch glycolate, hypromellose and sunflower oil. For other contraindications and cautions, please refer to the Potential Herb-Drug Interactions Chart. Please consult the actual product label for the most accurate product information. *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.