Canine Immune System Support, 3.9 oz (110 g)

Canine Immune System Support is a supplement that supports dogs' immune system function, endocrine health, and provides nutritional and biochemical support. Provides nutritional and biochemical support for healthy immune system Supports healthy immune system function Supports immune cell health Supports endocrine health Supports healthy inflammatory processes Provides antioxidant support Beneficial for dogs responding to common environmental challenges How the Canine Immune System Works A dog’s immune system is a complex array of cells that are found throughout the body. Immune cells are designed to work in conjunction with other cells to provide a defense against unwanted invaders. The complexity of a dog’s immune system requires a multidimensional approach of nutritional factors. The nutritional support of the immune system is directed at facilitating normal function and is not intended to be suppressive or stimulating. How Zinc Supports Canine Immune Health Zinc plays a vital role in immune cell signaling. Zinc homeostasis influences immune cell activity, function, and development by directly influencing their formation or altering signal protein secretion.1-6 How Kelp Supports the Canine Immune System Kelp is a whole food source of iodine. Iodine is thought to support the function of  immune cells.7 Iodine also indirectly possesses antioxidant activity.8 Citations Wellinghausen, N., Kirchner, H. & Rink, L. The immunobiology of zinc. Immunology today 18, 519-521 (1997). Ibs, K.H. & Rink, L. Zinc-altered immune function. The Journal of nutrition 133, 1452s-1456s (2003). Maywald, M., Wessels, I. & Rink, L. Zinc Signals and Immunity. International journal of molecular sciences 18(2017). Kitamura, H., et al. Toll-like receptor–mediated regulation of zinc homeostasis influences dendritic cell function. Nature Immunology 7, 971-977 (2006). Maares, M. & Haase, H. Zinc and immunity: An essential interrelation. Arch Biochem Biophys 611, 58-65 (2016). Wessels, I., Maywald, M. & Rink, L. Zinc as a Gatekeeper of Immune Function. Nutrients 9(2017). Venturi, S. Current Chemical Biology 5, 155-162 (2011). Venturi, S. Evolutionary significance of iodine. Current Chemical Biology 5, 155-162 (2011). Indications for Use For use in dogs. To support immune system. Directions for Use:  Administer orally. Best if given with food. A1610 Dose Schedule: Includes 1/8 tsp. scoop. 81 scoops per container. Dog Weight Daily Schedule (1 scoop = 1/8 tsp.) 1-10 lbs 1/8 tsp.       or     1 scoop         1x 11-20 lbs 1/8 tsp.       or     1 scoop         2x 21-40 lbs 1/4 tsp.       or     2 scoops       2x 41-60 lbs ½ tsp.         or     4 scoops       2x 61-80 lbs 3/4 tsp.       or     6 scoops       2x >80 lbs 1 tsp.          or     8 scoops     2x A1660 Dose Schedule: Includes 1/2 tsp. scoop. 74 scoops per container. Dog Weight Daily Schedule (1 scoop = 1/8 tsp.) 1-10 lbs 1/8 tsp.       or     0.25 scoop         1x 11-20 lbs 1/8 tsp.       or     0.25 scoop         2x 21-40 lbs 1/4 tsp.       or     0.5 scoops         2x 41-60 lbs ½ tsp.         or     1 scoops            2x 61-80 lbs 3/4 tsp.       or     1.5 scoops       2x >80 lbs 1 tsp.          or     2 scoops      2x A 1/8 tsp scoop is included with the small canine powder bottles, and a 1/2 tsp scoop is included with the large canine powder bottles. Suggested Use: See dosage schedule Special Information: With EpiCor® dried yeast fermentate, a registered trademark of Embria Health Science, LLC. Warnings: For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately. Cautions: Safe use in pregnant animals or animals intended for breeding has not been proven. If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian. Nutrients & Ingredients Amount per 1/8 tsp (370 mg): Dried yeast fermentate (EpiCor®)            33 mg Zinc (Zn amino acid (rice) chelate)             1 mg Vitamin E (Sunflower oil)                         0.3 mg Iodine (Kelp)                         0.03 mg Proprietary Blend                                 290 mg Bovine spleen, bovine spleen PMG™ extract, bovine thymus PMG™ extract, bovine thymus Cytosol™ extract, nutritional yeast, black currant (seed) oil, ashwagandha (Withania somnifera), organic shiitake mushroom powder, organic reishi mushroom powder, and eleuthero (Eleutherococcus senticosus). Please consult the actual product label for the most accurate product information. *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.