RENEFIL ULTRA PLUS

RENEFIL ULTRA PLUS is a powerful cross-linked hyaluronic acid (HA)-based filler enhanced with polynucleotides (PN) and lidocaine, designed for deep facial volumization and contouring. This hybrid formulation is ideal for patients requiring structural support, especially in areas such as the jawline, chin, temples, and deep nasolabial folds. As the densest and most robust option in the Renefil line, ULTRA PLUS delivers long-lasting lift, defined contours, and bio-revitalizing effects. It features a particle size of 1,000 μm, HA concentration of 20 mg/mL, and PN at 1.875 mg/mL, creating a synergistic blend of volumizing and regenerative action. With 0.3% lidocaine, patients experience improved comfort during injection. RENEFIL ULTRA PLUS Key Features and Benefits RENEFIL ULTRA PLUS is built for performance—designed to deliver dramatic yet natural volume, improve skin structure, and stimulate collagen regeneration. Its rheological profile ensures high viscosity and elasticity, resulting in excellent molding and durability with low injection force. Core Benefits: High volume retention for up to 12–14 months Restores structure in aging or volume-deficient areas Promotes collagen synthesis and skin regeneration High cohesiveness prevents product migration Smooth injection experience with lidocaine for patient comfort Ideal for facial contouring, lifting, and reshaping The filler combines the advantages of monophasic and biphasic gels, offering both strong lift capacity and easy injectability. RENEFIL ULTRA PLUS Composition RENEFIL ULTRA PLUS contains a specialized combination of active ingredients that deliver both immediate volumizing and long-term regenerative benefits. Per 1 mL: Cross-Linked Hyaluronic Acid (CL-HA): 20 mg Polynucleotides (PN): 1.875 mg Lidocaine Hydrochloride: 3 mg (0.3%) This triple-action formulation is stabilized through Renefil’s proprietary 4L™ Technology for purity, biocompatibility, and optimal rheology. RENEFIL ULTRA PLUS Intended Purpose / Indications RENEFIL ULTRA PLUS is formulated to address severe facial volume loss, deep wrinkles, and the need for facial sculpting. It provides structural support in deep facial tissues and helps restore youthful contours. Primary Indications: Jawline definition Chin projection Temple hollowness Mid-face volumization Deep nasolabial folds Zygomatic contouring It is particularly well-suited for patients seeking visible lifting effects and facial reshaping. RENEFIL ULTRA PLUS Injection and Treatment Areas Due to its high density and large particle size (1,000 μm), this filler is intended for use in the deep dermis or subcutaneous tissue. Recommended Treatment Areas: Chin Jawline Temples Cheeks Deep nasolabial folds Needle Size: 27G Injection Depth: Deep dermis to subcutaneous layer Texture: Dense and elastic for high lift capacity RENEFIL ULTRA PLUS Reconstitution and Preparation Guidelines RENEFIL ULTRA PLUS is supplied in a ready-to-use pre-filled syringe, requiring no reconstitution. The product should be prepared under aseptic conditions. Preparation Steps: Allow syringe to reach room temperature before injection Open packaging using sterile gloves Attach provided 27G needle Expel small amount to remove air and confirm smooth flow RENEFIL ULTRA PLUS Administration and Dosage This product is intended for use by qualified professionals trained in advanced dermal filler techniques and familiar with deep facial anatomy. Recommended Techniques: Linear threading Depot injection Fanning (for contouring zones) Dosage Guidelines: Start with 0.5 mL to 1.5 mL per area Maximum: 2 mL per session, depending on treatment goals Massage gently only if necessary to mold the product RENEFIL ULTRA PLUS Storage Instructions To preserve the integrity of the product, RENEFIL ULTRA PLUS should be stored under controlled conditions. Storage Guidelines: Store between 2°C and 25°C Avoid freezing Protect from direct light and heat Use before the expiry date indicated on the packaging RENEFIL ULTRA PLUS Contraindications RENEFIL ULTRA PLUS should not be used in patients with certain allergies, sensitivities, or underlying medical conditions. Contraindicated In: Allergy to HA, PN, or lidocaine Active skin infections or inflammation in treatment areas Autoimmune diseases Pregnancy or breastfeeding Individuals with bleeding disorders or undergoing anticoagulant therapy RENEFIL ULTRA PLUS Precautions and Warnings RENEFIL ULTRA PLUS should be injected with care to avoid serious complications and ensure optimal results. Key Warnings and Precautions: Do not inject into blood vessels Avoid using in periorbital areas Do not mix with other dermal fillers in the same area Monitor patients for immediate hypersensitivity reactions Be cautious in patients with scarring disorders Only trained professionals with knowledge of vascular anatomy should perform deep facial injections. RENEFIL ULTRA PLUS Post-Treatment Care To promote recovery and maintain aesthetic results, patients should follow simple post-care guidelines. Post-Treatment Recommendations: Avoid strenuous activity for 24 hours Refrain from heat exposure (sauna, sun) for 48 hours Apply cold compress if swelling occurs Avoid facial massage or pressure on treated areas Delay makeup use for 12–24 hours RENEFIL ULTRA PLUS Side Effects and Adverse Reactions The product is formulated for high tolerability, but as with any injectable, side effects can occur. Common Side Effects: Mild redness, swelling, or bruising Temporary tenderness or lumps Rare Side Effects: Granuloma formation Infection Vascular occlusion (emergency management required) All adverse reactions should be documented and reported to health authorities or the distributor. RENEFIL ULTRA PLUS Patient Eligibility RENEFIL ULTRA PLUS is intended for adults who desire non-surgical facial enhancement with durable, structural improvements. Eligibility Criteria: 18 years and older No recent facial surgery or active dermatological conditions No history of allergy to filler ingredients Not pregnant or breastfeeding Adequate health status for elective cosmetic procedures RENEFIL ULTRA PLUS Follow-Up and Maintenance Longevity is one of the strongest attributes of RENEFIL ULTRA PLUS. Patients benefit from a reduced number of sessions per year. Maintenance Guidelines: Results typically last 12 to 14 months Evaluate at 6 months for possible touch-up Annual repeat treatments recommended for sustained contour RENEFIL ULTRA PLUS Manufacturer and Regulatory Information RENEFIL ULTRA PLUS is developed and produced by BMI Korea Co., Ltd., and complies with international safety and quality standards. Manufacturer Information: Company: BMI Korea Co., Ltd. Location: Jeju-do, South Korea Certifications: CE 2020-MDD/05-095, ISO 13485:2016 Patents: Registered in USA, EU, Korea, Japan, Russia, China Each syringe includes a batch number and expiry date to ensure traceability and compliance. RENEFIL ULTRA PLUS FAQ Is RENEFIL ULTRA PLUS ideal for jawline sculpting? Yes, its high-density formulation is perfect for deep contouring such as jawline, chin, and cheeks. How long do the effects last? Up to 14 months, depending on metabolism, lifestyle, and injection technique. Is the injection painful? Discomfort is minimized due to the 0.3% lidocaine content. How soon will I see results? Immediately after injection, with improved results as swelling subsides within a few days. Can it be combined with other treatments? Yes, but not in the same area or session with other injectables. Always consult your practitioner.