Quiessence®

Horses and ponies that are nervous, tense, show an inability to learn and concentrate, have tight, tense muscles, are slow to warm up and have sore or tight backs can show improvement when given Quiessence®. Giving additional Magnesium and Chromium to cresty-necked, insulin resistant, founder prone horses and ponies may help reduce the tendency to develop endocrine-related laminitis. All sizes with Free Shipping in Continental U.S. (via USPS for small sizes, and UPS for others).* ---- Quiessence® provides high levels of Magnesium and Chromium in a pelleted and palatable form.  Quiessence® is a supplement that was formulated for horses to help support normal glucose metabolism, promote balanced behavior, and maintain relaxation in horses. Research shows that on a cellular level, within both horses and humans, Magnesium works closely with Potassium and Calcium. The lack of Magnesium in the body can result in low Potassium levels which can often lead to further health concerns. By supplementing Magnesium, especially for horses in a competitive lifestyle, may help support normal muscle function and help with tight sore muscles. Magnesium is primarily stored within the muscles in both humans and animals, so a lack of this mineral can lead to the reabsorption of this stored Magnesium, which can result in multiple neuromuscular issues such as muscle tightness, soreness or even injury. Therefore, the working muscles of a horse can certainly benefit from supplemented Magnesium, especially horses that are in a competitive lifestyle and those who are more susceptible to having tight sore muscles.           Quiessence® promotes a sense of relaxation and mental alertness without drowsiness. Horses that tend to express nervousness, muscular tension, inability to relax, irritability, hyper-sensitivity to touch or sounds, and poor memory retention can benefit from Quiessence® ,as it supports both physical and mental performance. Since Magnesium plays an important role in nerve function, this product may help those tense, spooky and inattentive horses regain a normal mental state and support normal balanced behavior.    Magnesium also promotes peripheral circulation and assists the body with normal clearance of glucose in horses. While Chromium has been shown to improve glucose clearance by supporting insulin sensitivity. Together these two minerals support glucose uptake by the cell and a normal metabolic rate. Quiessence® provides both of these minerals and can help horses and ponies that are cresty-necked and insulin resistant by helping to maintain blood glucose levels within normal ranges and assist the body with normal clearance of glucose. Active Ingredients: Magnesium Oxide, Magnesium Proteinate, Chromium Propionate Each ounce (scoop) provides: A proprietary blend of Magnesium Oxide and Magnesium Propionate: 8 grams (providing 4 mg of elemental magnesium). Chromium Propionate: 0.65 mg Inactive Ingredients: Artificial Banana Flavoring, Artificial Sweetener, Distillers Grains, Lignin Sulfonate, Propionic Acid (preservative), Propylene Glycol, Silicon Dioxide, Sodium Chloride, Vegetable Oil, Wheat Middlings  Feeding Directions Administer  2 to 4 scoops (ounces) per day or as recommended by your veterinarian or nutritionist.  Quiessence® may be given on an as needed basis as well. Cautions: Magnesium should not be given to horses with impaired kidney function or those with restricted water intakes. Chromium should not be given to horses with PSSM/EPSM. Client Testimonial Take a look at this testimonial that sums it up and reflects what I hear from many horseowners: "Taweela is not just a horse, she is my buddy and lifelong friend. I bought her when she was 18 months, and she is now 13 years young, which is the prime of life for an Arabian. Taweela is a high-level endurance performer who lives to see what is around the next corner. For endurance enthusiasts, this is the horse to have. However, with all of her wonderful traits, Taweela has a few challenge areas. The first is that after a Winter break, when Spring comes around and she is out on pasture for a short time, she starts getting obese. Her neck gets extremely cresty, and if not acted on quickly, she could founder. The second challenge is that she is extremely high-strung and nervous. She actually paces in the trailer and while we are 'standing' in place. She can be quite a handful, and doesn't seem to calm down even after a long ride. The third challenge is that the muscles on the entire length of her back have a hard time relaxing after a ride. I originally attributed this to saddle fit, and have spent thousands of dollars on a special saddle and all sorts of special pads. I have just accepted these things about her and dealt with them over the years because she is worth the extra effort, and I love her. Enter Quissence. I saw Dr. Getty's ad for Quiessence on her Web site, and decided to try it. I used the maximum dose on her until the crest in her neck started going down and getting softer. She also started getting calmer. She seemed to be a lot more relaxed. This took about 2 weeks. I then switched to the normal dose. The change has been amazing. Taweela is still the go-go girl I know and love, but she is so much more calm. She doesn't go crazy on the road home, and recently, after a short ride, she walked almost all the way home with a loose rein. I also checked her back after the ride, and there was no stiffness. I did not know that an imbalance in Magnesium could cause so many problems, not only physical but mental as well. Quiessence pellets are palatable and she eats every one. Taweela and I now have a much better relationship because she is able to focus more and relax. Thanks Dr. Getty!" ~ Barbara P., Oregon Sizing, Price and Serving Details 5 lb bag 40 two-ounce servings $48.95 14 lb bag112 two-ounce servings $99.95 16 lb pail 128 two-ounce servings $149.95 50 lbs (sewn bag) 400 two-ounce servings $268.95 Shipping Information *Quiessence is shipped via UPS (via USPS for 5 lb bags) within two days. Free shipping is offered anywhere within the continental U.S. Shipping to Hawaii and Alaska will incur additional shipping charges. Please email GettyEquineNutrition@gmail.com or call 940-487-7161 before ordering for a shipping quote to these areas. Canadian Orders: For orders in Canada, please contact Dr. Getty for assistance in finding dealers in Canada.  Interested in Auto-Ship? Send Getty Equine Nutrition an email at GettyEquineNutrition@gmail.com or call 940-487-7161. Magnesium Absorption By Dr. Melyni Worth, Foxden Equine Magnesium absorption in equines has not been fully investigated and most of the information that we have is extrapolated from ruminant studies, rat studies and human studies. There is considerable difference in Magnesium absorption in each of these species, and thus we do not, at this time, fully understand the exact sites and mechanisms of Mg absorption in the horse. In humans there appears to be 3 different pathways of absorption, there is passive diffusion, an active diffusion and solvent drag. The bulk of Mg absorption (in humans) occurs in the small intestine, with a secondary site in the descending colon. In horses diffusion uptake is believed, to be primarily in the colons, however there is also some uptake in the distal small intestine. The solvent drag uptake is believed to be primarily in the small intestine. The mechanisms of diffusion both passive and active require the presence of Mg and Ca ions in the gut lumen to be in a ratio to one another, as one of the transport mechanisms (the active) is not specific to either Mg or Ca, but picks up bivalent cations indiscriminately. The ‘solvent drag’ mechanism includes the use of the mineral ion bound to proteins, as the proteins are picked up actively they ‘carry’ the mineral ion along with them. This mechanism is particularly effective if the Mg ion is bound to an essential amino-acid, as the essential aa’s are most actively absorbed. Thus Mg bound to methionine, or aspartate is absorbed faster and more efficiently, since those aa’s are more efficiently absorbed. This pathway acts along side the two diffusion pathways and produces a considerable increase in the amount of Mg absorbed from the gut. Thus to supply the Mg most efficiently, it is best to supply the Mg as both a salt and as a proteinate, this means that the Mg can be absorbed by all 3 pathways. Thus increasing the amount that is absorbed in a given time and for a given dose. Miner Electrolyte Metab. 1990;16(2-3):174-80. Site and mechanism of intestinal magnesium absorption. Hardwick LL1, Jones MR, Brautbar N, Lee DB. Despite considerable research on magnesium (Mg) absorption there is still uncertainty regarding the site and mechanism of intestinal Mg transport. A careful review of the literature indicates that while Mg is absorbed throughout the intestine, the predominate site is the distal small intestine. There are three mechanisms by which Mg has been shown to cross the intestine:passive diffusion, solvent drag, and active transport. The importance of each of these mechanisms to total Mg absorption is discussed. Studies in both humans and experimental animals indicate that passive diffusion through the paracellular pathway accounts for the majority of Mg absorbed. Investigators have also consistently demonstrated the existence of a saturable component. Studies in everted gut sacs, however, have failed to demonstrate that Mg is actively transported against a concentration gradient in young or adolescent rats. Recent studies using the Using chamber have documented that Mg is actively transported in the descending colon. Magnes Res. 1991 Mar;4(1):9-22. New clinical and experimental aspects of intestinal magnesium transport. Karbach U1, Feldmeier H. Author information Abstract Mg transport across various segments of the rat small and large bowel was measured in the absence of electrochemical gradients and using the voltage clamp technique. In the mucosa-to-serosa (ms) Mg flux across the duodenum, ileum, and colon a cellular part is involved, amounting to 40-70% of the total ms Mg flux measured across the short-circuited tissue. However, serosa-to-mucosa (sm) Mg flux is purely passive, suggesting that net Mg transport is largely determined by convectively driven Mg flux across the paracellular pathway. Mg is absorbed across the colon and ileum but in the duodenum paracellularly it is secreted due to an 'anomalous solvent drag effect'. Mg in the caecum decreases cellular ms Ca transport but in the other segments only passive ms Ca flux is reduced by a decrease of the paracellular permeability for Ca, or by a Mg-induced decrease in water absorption. Mg transport across all segments is insensitive to 1,25(OH)2D3. Dexamethasone abolishes cellular Ca transport but stimulates paracellular ms Mg flux in the duodenum. It is concluded that in the rat (a) Mg and Ca are transported by distinct cellular and paracellular mechanisms; (b) Mg transport is largely confined to the paracellular pathway; (c) the ileum and the colon are the major sites for the gut regulation of Mg homeostasis.