PLINEST® FAST (2ml)

PLINEST FAST Product Description PLINEST FAST is a sterile injectable dermal biorevitalization treatment based on PN-HPT™ (Polynucleotides Highly Purified Technology). Developed by Mastelli, this advanced formulation is engineered for rapid skin regeneration, providing both immediate hydration and long-term improvement in skin structure. Formulated with highly purified DNA polymers, PLINEST FAST is ideal for intensive treatments, skin priming, or as a preparatory procedure before other aesthetic interventions like laser, fillers, or microneedling. It is especially suitable for patients seeking quick recovery, brightening, and visible improvement in skin texture, with high biocompatibility and minimal downtime. PLINEST FAST Key Features and Benefits PLINEST FAST delivers fast-acting bio-revitalization to improve skin’s resilience and elasticity. It promotes natural cellular regeneration, enhances hydration, and restores skin tone and luminosity, making it ideal for patients with dull, tired, or dehydrated skin. Key Benefits: Accelerated hydration and smoothing of the skin Boosts fibroblast activity and collagen production Prepares skin for other treatments with priming effect Enhances outcomes of aesthetic procedures Non-invasive, quick to apply, and virtually painless Visible improvement in skin firmness and elasticity Appropriate for younger and mature skin types PLINEST FAST Composition The PLINEST FAST formulation combines high molecular weight polynucleotides with a sterile, viscoelastic gel base, ensuring deep tissue integration and cellular activation. Composition (per 2ml syringe): PN-HPT™ (Polynucleotides Highly Purified Technology): 15–20 mg (exact concentration may vary by protocol) Sterile, non-pyrogenic, viscoelastic gel No lidocaine, ensuring maximum tolerability even in sensitive areas The DNA used in PN-HPT™ is derived from natural sources, fractionated and purified to produce a biologically active and safe formulation. PLINEST FAST Intended Purpose / Indications PLINEST FAST is intended for intensive revitalization treatments aimed at improving hydration, elasticity, and skin priming. It is suitable for both standalone therapy and in combination with other aesthetic modalities. Primary Indications: Dull or dehydrated skin Early signs of aging and laxity Skin priming before laser, RF, fillers, or surgery Fine wrinkles and superficial lines Prevention of premature aging It is particularly effective on the face, neck, and décolleté, with noticeable improvements even after a single cycle. PLINEST FAST Injection and Treatment Areas PLINEST FAST is designed for intradermal injection, targeting areas of low elasticity, rough texture, or fatigue-related dullness. Recommended Treatment Areas: Full face Neck Décolleté Hands Forehead and cheek zones (pre-laser or filler) Injection Depth: Intradermal Technique: Micro-droplet or linear retrograde Needle Size: Typically 30G ½ inch needle Session Volume: 2ml per session (1 syringe) PLINEST FAST Reconstitution and Preparation Guidelines PLINEST FAST comes in a ready-to-use pre-filled syringe and requires no additional reconstitution or dilution. It is prepared under aseptic medical conditions. Preparation Instructions: Allow product to reach room temperature before use Maintain sterility throughout handling Attach provided needle securely Prime syringe before injection PLINEST FAST Administration and Dosage PLINEST FAST is administered via intradermal injections by trained healthcare professionals. The protocol can be tailored based on patient age, skin condition, and intended outcome. Standard Protocol: 1 session every 14–21 days Total of 3 sessions per treatment cycle Maintenance: 1 session every 2–3 months Injection Techniques: Micro-droplets of 0.1–0.2 ml spaced evenly Linear retrograde injections along relaxed skin tension lines Do not exceed 2 ml per session, unless advised by a physician. PLINEST FAST Storage Instructions To maintain the stability and sterility of PLINEST FAST, it should be stored under regulated conditions. Storage Guidelines: Store at 2°C to 25°C Do not freeze Protect from light and heat Use before indicated expiry date PLINEST FAST Contraindications Though highly safe and biocompatible, PLINEST FAST is contraindicated in patients with specific medical risks or hypersensitivities. Do Not Use In: Known allergy to polynucleotides Presence of infections or inflammation at injection site Pregnant or breastfeeding women Patients with autoimmune disorders Those on immunosuppressive therapy PLINEST FAST Precautions and Warnings When used correctly, PLINEST FAST has an excellent safety profile, but certain precautions must be followed to avoid complications. Precautions: Avoid injecting into vascular structures Use only in clean, aseptic conditions Do not mix with other injectables in the same syringe Avoid aggressive massaging post-treatment Monitor for hypersensitivity in the first 24 hours PLINEST FAST Post-Treatment Care Aftercare is important to maximize outcomes and minimize side effects. Post-Treatment Recommendations: Avoid makeup, UV exposure, and heat for 24–48 hours Do not apply pressure or massage treated areas Use cold compresses for swelling or redness Follow physician’s instructions for any additional skin care PLINEST FAST Side Effects and Adverse Reactions PLINEST FAST has undergone clinical safety evaluations and shows a low incidence of side effects, thanks to its high purification and bio-compatibility. Common Side Effects: Mild redness, swelling, or itching Temporary bruising at injection sites Rare Side Effects: Nodules or localized inflammation Infection (extremely rare) Allergic reaction (if patient is sensitized) Patients are advised to report any unexpected or lasting symptoms. PLINEST FAST Patient Eligibility PLINEST FAST is ideal for a wide patient base, including young individuals for prevention and mature patients for correction and support. Eligibility Guidelines: Patients aged 18 and above No active infections, chronic dermatologic diseases, or systemic illness Not currently pregnant or breastfeeding No history of severe allergic reactions or autoimmune disorders PLINEST FAST Follow-Up and Maintenance Ongoing treatments help maintain and amplify the effects of PLINEST FAST, especially for patients with aging skin or environmental skin damage. Recommended Maintenance: Initial cycle: 3 sessions every 2–3 weeks Long-term: 1 session every 3 months Can be combined with laser, needling, peels, and fillers PLINEST FAST Manufacturer and Regulatory Information PLINEST FAST is manufactured by Mastelli Srl, a recognized innovator in aesthetic regenerative medicine. It meets the highest standards for quality and safety. Manufacturer Information: Company: Mastelli Srl Location: Italy Medical Classification: CE-certified Class III medical device Packaging: 1 x 2ml pre-filled syringe with 2 x sterile 30G needles Traceability: Each syringe has a batch number and expiry date PLINEST FAST FAQ How soon will I see results? Many patients see noticeable skin improvement after just one session, with full benefits developing over 2–4 weeks. Is the treatment painful? Pain is minimal. The use of fine 30G needles ensures a gentle injection experience. Can it be used with other treatments? Yes, PLINEST FAST is often used to prime the skin before other procedures like lasers or microneedling. What age group is this best for? It’s suitable for both preventive care in younger patients and restorative care in mature skin. How long do results last? Results can last 4–6 months, with longer effects seen when used regularly or in combination with other modalities.