PE-22-28

PE-22-28 Chemical Information: Chemical Name: Spadin-derived heptapeptide (Gly-Val-Ser-Trp-Gly-Leu-Arg) Molecular Formula: C₃₅H₅₅N₁₁O₉ Molecular Weight: ~773.89 g/mol CAS Number: 1801959-12-5 Compound Class: Synthetic peptide (spadin analogue, heptapeptide) Product Description: PE-22-28 is a synthetic heptapeptide corresponding to residues 22–28 of spadin, a naturally occurring peptide fragment derived from the sortilin propeptide. The sequence represents a shortened analogue of the parent peptide. PE-22-28 is produced via solid-phase peptide synthesis (SPPS) and supplied as a lyophilized powder intended exclusively for controlled in-vitro laboratory research by qualified professionals. This product is not formulated for clinical, diagnostic, or therapeutic use. Research Applications: In-vitro investigation of TREK-1 (two-pore-domain potassium channel) modulation in cell-based assay systems Laboratory studies of sortilin-derived peptide structure–activity relationships Comparative evaluation of shortened spadin analogues for binding affinity and stability Analytical method development and reference characterization for sequence-specific peptides Storage and Handling: Store lyophilized material at -20 °C for long-term stability Reconstituted solutions should be stored at 2–8 °C and used promptly Protect from light, heat, and repeated freeze–thaw cycles Handle using appropriate laboratory safety and aseptic techniques Product Specifications: Purity: ≥99% (HPLC Certified) Appearance: White to off-white lyophilized powder Solubility: Soluble in suitable laboratory agents Form: Lyophilized powder Compliance Notice: PE-22-28 is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.