NCA Plus

Formula Purposes & Benefits NAC Plus is developed based on cutting-edge scientific research and expert formulation to support healthy detoxification, antioxidant status, respiratory health, and glutathione status in the body.   Our formula is the choice for doctors seeking to enhance their patients’ well-being. Utilize our formula for superior patient well-being. Our formula includes the NAC Excel Blend, enriched with organic curcumin, organic milk thistle, and green tea extract. With this powerful combination of phytonutrients, empower your patients with comprehensive antioxidant support. Our formula is proudly made in the USA in an FDA registered facility, following Good Manufacturing Practices (GMP) standards. Our commitment to excellence is reflected in the fact that only 4% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient N-Acetyl Cysteine ●        May support immune health, healthy detoxification, and increase antioxidant function (351,352).   ●        May support immune health via increases of L-Glutathione production (master antioxidant) (351,352). ●        May support detoxification via enhanced toxin clearing from the liver (351,352). Organic Turmeric ●        May support antioxidant, cardio-protective, anti-inflammatory, anti-microbial, nephro-protective, hepato-protective, immunomodulatory, and anti-rheumatic effects (123).   ●         May reduce inflammation via decreases of inflammatory markers such as c-reactive protein, interleukin 6, tumor necrosis factor, and decreased cytokine production (123). ●        May support joint health via decreases in connective tissue inflammation and improved pain in individuals with osteoarthritis (122). ●        May support blood sugar regulation via increased pancreatic beta cell function and improved insulin sensitivity (121). ●        May support cardiovascular and liver health via reduced accumulation of advanced glycation end products (AGE), reduced lipid peroxidation, and improved vascular function. ●        Curcumin may exhibit antioxidant activity via scavenging of superoxide anion (∙O2−∙) and hydroxyl radicals (∙OH) (scavenging of inflammation molecules) (118,119). ●        Curcumin may modulate breast carcinogenesis through its effect on cell cycle and proliferation, apoptosis, senescence, cancer spread and angiogenesis (119). ●        May target cancer growth pathways such as the NFkB, PI3K/Akt/mTOR, MAPK and JAK/STAT (119). Organic Milk Thistle ●        May support liver health, aids as antioxidants, and reduces inflammation (345).   ●        May support liver health via high amounts of Silymarin which reduces lipid peroxidation and inhibits binding of toxins to the hepatocyte cell membrane receptors (345). Green Tea Extract ●        A potent polyphenolic antioxidant that may support blood pressure, insulin sensitivity, and metabolic health (25).   ●         Contains high concentration of ECGC that may reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise. (25). ●        Potent anti-inflammatory compound that may support glutathione production and inhibition of pro-inflammatory markers (cytokines). (26). ●        May reduce oxidative stress (chronic inflammation in the body) (26).   Proper Use of This Supplement Suggested Use:  Take 1 capsule, 2 times daily or as directed by a health professional.   Our Formula Vs Other Formulas on the Market. 1. Our formula is GMP certified and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. 2. High quality NAC, organic turmeric, green tea, and organic milk thistle in a bioavailable and efficaciously dosed formula. 2. Uses cheap synthetic NAC, turmeric, green tea, and milk thistle that may have heavy metals due to poor product quality and fillers.   Sources: Rothenberg, D. O., Zhou, C., & Zhang, L. (2018). A Review on the Weight-Loss Effects of Oxidized Tea Polyphenols. Molecules (Basel, Switzerland), 23(5), 1176. https://doi.org/10.3390/molecules23051176 Bogdanski, P., Suliburska, J., Szulinska, M., Stepien, M., Pupek-Musialik, D., & Jablecka, A. (2012). Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutrition research (New York, N.Y.), 32(6), 421–427. https://doi.org/10.1016/j.nutres.2012.05.007 Haidari, F., Samadi, M., Mohammadshahi, M., Jalali, M. T., & Engali, K. A. (2017). Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women. Asia Pacific journal of clinical nutrition, 26(6), 1048–1054. https://doi.org/10.6133/apjcn.022017.03 Chilelli, N. C., Ragazzi, E., Valentini, R., Cosma, C., Ferraresso, S., Lapolla, A., & Sartore, G. (2016). Curcumin and Boswellia serrata Modulate the Glyco-Oxidative Status and Lipo-Oxidation in Master Athletes. Nutrients, 8(11), 745. https://doi.org/10.3390/nu8110745 Barzegar, A., & Moosavi-Movahedi, A. A. (2011). Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin. PloS one, 6(10), e26012. https://doi.org/10.1371/journal.pone.0026012 Banik, U., Parasuraman, S., Adhikary, A. K., & Othman, N. H. (2017). Curcumin: the spicy modulator of breast carcinogenesis. Journal of experimental & clinical cancer research : CR, 36(1), 98. https://doi.org/10.1186/s13046-017-0566-5 Suhett, L. G., de Miranda Monteiro Santos, R., Silveira, B., Leal, A., de Brito, A., de Novaes, J. F., & Lucia, C. (2021). Effects of curcumin supplementation on sport and physical exercise: a systematic review. Critical reviews in food science and nutrition, 61(6), 946–958. https://doi.org/10.1080/10408398.2020.1749025 Pivari, F., Mingione, A., Brasacchio, C., & Soldati, L. (2019). Curcumin and Type 2 Diabetes Mellitus: Prevention and Treatment. Nutrients, 11(8), 1837. https://doi.org/10.3390/nu11081837 Ashtary-Larky, D., Rezaei Kelishadi, M., Bagheri, R., Moosavian, S. P., Wong, A., Davoodi, S. H., Khalili, P., Dutheil, F., Suzuki, K., & Asbaghi, O. (2021). The Effects of Nano-Curcumin Supplementation on Risk Factors for Cardiovascular Disease: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials. Antioxidants (Basel, Switzerland), 10(7), 1015. https://doi.org/10.3390/antiox10071015 Mata, I., Mata, S., Menezes, R., Faccioli, L. S., Bandeira, K. K., & Bosco, S. (2020). Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Critical reviews in food science and nutrition, 1–15. Advance online publication. https://doi.org/10.1080/10408398.2020.1798353 Eisvand, F., Razavi, B. M., & Hosseinzadeh, H. (2020). The effects of Ginkgo biloba on metabolic syndrome: A review. Phytotherapy research : PTR, 34(8), 1798–1811. https://doi.org/10.1002/ptr.6646 Millea P. J. (2009). N-acetylcysteine: multiple clinical applications. American family physician, 80(3), 265–269. Rushworth, G. F., & Megson, I. L. (2014). Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits. Pharmacology & therapeutics, 141(2), 150–159. https://doi.org/10.1016/j.pharmthera.2013.09.006