Methylation Supplements: L Methylfolate + B12 Sublingual

Description Get 2 of Methyl-Life’s® foundational methylation products for neuro-protection.  This active-nutrients package contains 2 chewable products targeting improved cognition and brain health: The purest L-Methylfolate (as shown in a recent study) The rare but well-tolerated form of B12 (as Hydroxy B12) Check out the details below regarding each product included in the bundle to learn more: Methylfolate 5 - Most stable & pure form of L-Methylfolate available for purchase Hydroxy B12 - Active B12 at 2.5 mg per tablet Dosage WARNING – How much is right for you to take? Talk to your doctor about what’s best for you. Before you purchase check out our dosage information to learn more about what some doctors recommend. And review our suggested methylation protocol as a potential step by step guide to some dosing options. How to snap the tablet in half – See how its done via video. First find the half hash line and face it away from yourself (with the back of the tablet facing your chest/stomach), then put both of your thumbs next to each other along the line (as if there were one on the back of the tablet). You want the half hash line facing away from you (not on the side of the tablet where your thumbs are). And then you should be able to break it in half along that line every time by simply applying pressure to snap it outwards, by pushing your thumbs away from you. This approach works far better than using a pill cutter, which seems to cause the tablet to crumble much more.  Research FAQ'S What is the right dosage for me? Check out our Dosage page to learn what some doctors are saying. And consider reviewing our Methylation Protocol page as one example of how someone could start taking the active methylation nutrients. What is the Methyl-Life® Brain Protect Bundle? The Methyl-Life® Brain Protect Bundle is a combination of two foundational methylation products specifically formulated for neuro-protection. It includes chewable supplements targeting improved cognition and brain health.  What do doctors have to say about MTHFR and how to treat it? Go to A Doctor Explains and listen to Dr. Neil Rawlins’ 51-minute seminar on MTHFR and the effects of Methylfolate.  How can I get more information on MTHFR? check out our Help for MTHFR Newbies page. Which products are included in the bundle? The bundle contains: Methylfolate 5: This product features the most stable and pure form of L-Methylfolate available for purchase, with a dosage of 5 mg per tablet. Hydroxy B12: This is the rare but highly tolerated form of B12, providing 2.5 mg of active B12 per tablet. What are the benefits of Hydroxy B12 for the brain? Hydroxy B12 is known for its neuroprotective properties and its ability to support healthy nerve function. With a dosage of 2.5 mg per tablet, it complements the cognitive support provided by Methylfolate. What can you do if you have high B12 blood test results? Dr. Amy Yasko and Nutritionist Cynthia Smith both suggest you can consider taking low dose lithium orotate (Cynthia Smith suggests approximately 4.6 mg pulsed a couple times a week before adding the B12 form in that’s most likely best for you). Who can benefit from using the Methyl-Life® Brain Protect Bundle? Individuals seeking to support cognitive function, enhance brain health, or protect against neurological decline may benefit from this bundle. It is particularly suitable for those with concerns about methylation support and brain health. How should the products in the bundle be consumed? Both Methylfolate 5 and Hydroxy B12 are chewable tablets, making them convenient for daily consumption. Follow the recommended dosage instructions provided with each product or consult a healthcare professional for personalized guidance.  I have my 23andme test results, how can I use those to know which form of B12 I might best tolerate? If you have your 23andme genetic test results, you can use those to help guide you as you try the specific B12 forms to see how they do for you. You’ll notice below that, according to Dr. Amy Yasko, the most well tolerated active form of B12 for folks seems to be hydroxocobalamin. Every single one of the genetic combinations she lists below should be able to tolerate B12 in the form of hydroxocobalamin (and this is why our methylation protocol suggests hydroxocobalamin as the B12 form to begin with): Folks with multiple COMT mutations tend to do very well with hydroxocobalamin (it helps mop up excess peroxynitrites which can cause problems) Folks with MTR & MTRR mutations may do well with methylcobalamin & adenosylcobalamin supplementation And Dr. Amy Yasko(https://dramyyasko.com/)talks about folks with a particular mutation status for COMT & VDR Taq as best needing the below forms of B12: COMT V158M VDR Taq B12 Types That Should Be Tolerated – – + + (TT) All 3 types of B12 – – + – (Tt) All 3 types of B12 with less Methylcobalamin – – – – (tt) Hydroxocobalamin and Adenosylcobalamin + – + + All 3 types of B12 with less Methylcobalamin + – + – Hydroxocobalamin and Adenosylcobalamin + – – – Hydroxocobalamin and Adenosylcobalamin + + + + Hydroxocobalamin and Adenosylcobalamin + + + – Hydroxocobalamin and Adenosylcobalamin + + – – Mostly Hydroxocobalamin