L-Methylfolate

as Quatrefolic ® (6S)-5-methyltetrahydrofolate, glucosamine salt] 1,700 mcg DFE (1,000 mcg) Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose and water), ascorbyl palmitate, L-leucine, and silica.  Does Not Contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, sesame, gluten, GMO, artificial colors, or artificial flavors.  Suggested Use As needed take 1 capsule daily with or without food, or use as directed by your healthcare provider. Do not take within 5 hours of bedtime as it may interfere with sleep. Warnings: Children and pregnant or lactating women should consult their healthcare professional for medical advice prior to use. Do not use it if the tamper seal is damaged. Consult a healthcare professional prior to use if you are taking any medications or undergoing treatment for any medical condition. Storage: Keep closed in a cool, dry place out of reach by children. More Info.  Folate is a water-soluble B vitamin that occurs naturally in food, such as leafy green vegetables, citrus fruits, dried beans, and peas. The methylated form, L-5-methylfolate (L-5-MTHF) requires no additional metabolic steps to be used by the body, and is often the preferred choice for those with absorption or metabolic defects. L-5-MTHF efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function. L-5-MTHF is easily absorbed and used by cells. It is the predominant folate in circulation and the only form of folate that can cross the blood-brain barrier. When first taking L-methylfolate, side effects are possible due to inefficient methylation, pre-existing inflammation or possible genetic deficiencies. Consult your health care professional for testing to determine the proper dose of L-methylfolate for your individual needs. Niacin may help to support folate processing, and may be helpful to have on hand to support the body’s metabolism of methylfolate if side effects occur. For a non-methylated form of folate that is still well-absorbed and utilized, consider Seeking Health's Folinic Acid Lozenges. For additional methylation support, consider Active B12 with L-5-MTHF. Allergy and Diet Information: L-5-MTHF is suitable for vegans or vegetarians. L-5-MTHF is free of dairy, egg, fish, shellfish, tree nuts, peanuts, wheat, soy, gluten, GMOs, artificial colors, artificial flavors, and artificial preservatives. L-5-MTHF meets or exceeds cGMP Quality Standards.