Calm Mind

Pure Encapsulations Calm Mind Promotes a Calm State of Mind Calm Mind combines two clinically studied botanical extracts, saffron (affron®) and curcumin (Theracurmin®), to support a positive mood, a calm state of mind, and emotional well-being. In a double-blind trial involving 128 adults self-reporting low mood, saffron (affron®, 28 mg/day) resulted in a significant decrease in negative mood and symptoms related to stress after 4 weeks compared to placebo. Other studies indicate that saffron also supports sleep with continued use. The regulation of mood and emotional state is influenced by the immune system, and emerging research suggests an impactful role of immune mediators known as cytokines. Lower plasma levels of certain cytokines, such as IL-6 and TNF-α, are associated with positive mood and emotional well-being. In preclinical models, curcumin moderates the production of the cytokines IL-1β, IL-6, and TNF-α.5,6 and moderates pro-inflammatory cytokine pathways in the brain. However, the low oral bioavailability of curcumin may limit its ability to support brain function.  Theracurmin® is 27 times more bioavailable than standard curcumin. In a study of 40 adults (51–84 years of age). Theracurmin® containing 90 mg curcumin twice daily for 18 months significantly improved short-term, verbal, and visual memory and attention. Key Benefits and Features:  Patients seeking support for mood and emotional well-being Patients experiencing occasional stress and/or sleeplessness  Supports emotional well-being Supports a positive mood and emotional outlook Promotes a calm state of mind Supports sleep with continued use Clinically studied saffron (affron®) Clinically studied curcumin (Theracurmin®) with 27x enhanced bioavailability  Ingredients Serving Size: 1 Vegetarian Capsule  Amount/Serving Theracurmin turmeric (Curcuma longa L.) extract (rhizome) (standardized to contain 30% curcumin)  300 mg Affron saffron (Crocus sativus) extract (stigma) (standardized to contain 3.5% Lepticrosalides) 15 mg Other Ingredients: Hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water), and ascorbyl palmitate.  Does Not Contain: Wheat, soy, dairy, egg, tree nuts, peanuts, gluten, artificial colors, artificial flavors, artificial sweeteners, coating, shellacs, GMOs, unnecessary binders, fillers, preservatives, magnesium stearate, trans fat, and hydrogenated oils.  Gluten-Free, Non-GMO, Vegetarian  Suggested Use As a dietary supplement, take 1 capsule, 2 times daily, between meals, or as directed by a health professional.  Warning: If you are pregnant or lactating, have any health conditions or are taking any medication, consult your healthcare professional before use. Keep out of the reach of children.  Storage: Store in a cool, dry place.  More Info.  Turmeric extract is derived from Curcuma longa L. rhizome and standardized for curcumin Saffron extract is derived from Crocus sativus stigma and standardized for Lepticrosalides Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil   Hypoallergenic plant fiber is derived from pine cellulose