Berberine 500+ | Dihydroberberine Weight Loss Support Formula (60 Servings)

4.5 ★from 800+ verified reviews 100,000+thyroid patients served Third-partytested, every batch 60 daysmoney back guarantee Why berberine for thyroid patients Designed for thyroid patients doing everything “right” without results Thyroid medication can fix your labs, but it doesn’t always fix your metabolism. That’s exactly why I created Berberine 500+. Its dual-action formula helps you switch your metabolism on, so you can: start burning fat instead of storing it, start feeling full instead of feeling hungry, and start seeing the scale drop instead of climb.* If your metabolism is as sluggish as your thyroid, Berberine 500+ may be the key to getting the results you’ve been working so hard for. Dr. Westin ChildsThyroid specialist and formulator 1 Your thyroid slows your metabolism You burn fewer calories at rest, so it’s easier to gain weight and harder to lose it. 2 Your body can’t use sugar as effectively A slow thyroid impacts how insulin works, leading to spikes that cause cravings, hunger, and fat storage.* 3 Berberine supports AMPK to help break the process AMPK activation tells your body to burn fat instead of store it. It’s the same enzyme activated by exercise.* What’s inside Research-backed ingredients Two forms of berberine at 200 mg each, plus 250 mg alpha lipoic acid, for immediate and sustained release activation of AMPK.* The actual label, straight off the bottle. Click to enlarge. Dihydroberberine as GlucoVantage, 200 mg per serving This plant-derived isoquinoline alkaloid activates a powerful enzyme known as AMP kinase, the same enzyme that is activated during exercise.

And it is the activation of this enzyme that provides the majority of the benefits associated with berberine use, including weight loss

, blood sugar control

, and lower cholesterol

. Berberine 500+ has been formulated with a downstream derivative known as dihydroberberine, which has been shown to be up to 5x more bioavailable than standard berberine. This means you get better results at lower dosages with reduced risk of side effects. Research shows that berberine may… Help you lose weight*

Improve insulin sensitivity*

Lower cholesterol*

Increase fatty acid oxidation*

Improve gut health* Increase mitochondrial density in skeletal muscle*

Activate brown fat*

Act as an anti-inflammatory agent* …making berberine a no-brainer for anyone seeking to lose weight. Berberine HCL 200 mg per serving You can think about dihydroberberine as an immediate-release form of berberine and berberine HCL as a delayed-release form. By using both versions, you get both immediate and long term benefits from berberine leading to prolonged activation of AMPK (the enzyme that makes berberine so powerful).

The result? Faster weight loss. Better insulin control.

Better blood sugar regulation.

And better cholesterol management.

Alpha lipoic acid 250 mg per serving This plant-derived short-chain fatty acid acts as an incredibly powerful antioxidant making it an effective treatment against oxidative-stress-associated diseases and conditions.

It works by neutralizing free radicals and regenerating other antioxidant factors such as vitamin C and vitamin E, which act to increase glutathione synthesis.

Because of these effects, research has shown that alpha lipoic acid may… Reduce body weight and fat mass*

Decrease appetite and food intake*

Enhance energy expenditure* Act as an anti-inflammatory agent* Improve insulin sensitivity*

Improve nerve health

Prevent vascular damage* …making it the perfect complementary ingredient to berberine for weight loss. GLP-1 activator supports your body’s own GLP-1* This all-natural GLP-1 stimulator may provide benefits to weight, satiety, appetite, and insulin without the need for a prescription or dangerous side effects.* Feel full sooner: supports the satiety signal between your gut and your brain.* Fewer cravings: support for appetite between meals.* Supports healthy insulin: the other half of the weight equation for thyroid patients.* Gentle on the stomach Gentler than standard berberine at effective doses. If it bothers your stomach, take it with food and that should solve the issue.* No stimulants, no jitters It works through AMPK, not caffeine.* No common allergens No wheat, gluten, yeast, soy, dairy, fish, shellfish, peanuts, tree nuts, or egg. Nothing artificial. Real-world patient outcomes What thyroid patients actually report Read the full Patient Outcomes Report for verbatim quotes, methodology, and limitations. 83.8%overall satisfaction 60.0%reported weight, appetite, or metabolic improvements 38.1%reported noticeable weight loss 15.2%reported blood sugar or clinical improvements “I have been using Dr. Childs’s Berberine 500+ and have lost 20 pounds! I have noticed more energy, less cravings and I’m much leaner.” ★★★★★Verified buyer✓ Verified purchaseBerberine 500+ ★★★★★ Lost 30 pounds this summer I have been on Berberine for 5 months. Hate to stop using it because I have lost 30 pounds this summer. I’ve already had a doctor appointment with blood tests, and A1C and cholesterol numbers have come down. Verified buyer ✓ Verified purchase ★★★★★ Jeans two sizes smaller I used this Berberine for a month and by the second week I was able to fit comfortably in my jeans. Six weeks later on Berberine I am wearing jeans two sizes smaller. Verified buyer ✓ Verified purchase ★★★★★ Cravings have noticeably gone way down I will continue taking this supplement as my cravings have noticeably gone way down. I take 1/2 dose in the AM and the other 1/2 in the PM. Helps me control my eating. Verified buyer ✓ Verified purchase ★★★★★ Makes me feel full on a little I love the Berberine. It really makes me feel full on a little. I give it a 5 out of 5. Patricia K. ✓ Verified buyer ★★★★★ A1C dropped from 6.8 to 5.3 I took this for three months and my A1C dropped from 6.8 to 5.3 and my fasting blood sugar was 94 instead of over 100. Cholesterol down to normal too! Verified buyer ✓ Verified purchase ★★★★★ Helped bring my energy back Thanks Dr. Childs, I do think the Berberine has helped bring my energy back to myself. It took several weeks, but I am happy with the results so far. Janet L. ✓ Verified buyer Read all 800+ reviews Add to cart · $53.99Or subscribe and pay $48.59. Free shipping either way. Frequently bought together Patients often pair it with these Thyroid Fat Burner Thyroid-safe, non-stimulating thermogenic that helps your body unlock stubborn fat cells so you can burn them for energy.* $44.99 · View Thyroid Leptin Balance Helps restore communication between your metabolism, hunger hormones, and thyroid pathways.* $49.99 · View Your new routine Simple dosing, impressive results 1 2 capsules in the morningWith or without food. 2 2 capsules in the eveningSteady 24-hour support.* 3 30 to 60 minutes from thyroid medsBefore or after both work. It can be combined with other weight loss supplements, metformin, and prescription weight loss medications. What should I expect? 4 weeks You may start to feel Fuller between meals, with fewer cravings and steadier energy.* 4-8 weeks You may start to see Changes in how your clothes fit and in your body measurements.* 12+ weeks Long-term support Some patients report changes in A1C, fasting blood sugar, and cholesterol at follow-up bloodwork.* How it compares See how Berberine 500+ compares Berberine 500+ Other thyroid supplements Thyroid medication Other berberine supplements Supports natural GLP-1 activation* ✓ ✕ ✕ ✕ Promotes healthy fat metabolism* ✓ ✕ ✕ ? Supports thyroid-related belly bloat* ✓ ✕ ✕ ✕ 5x more bioavailable formula ✓ ✕ ✕ ✕ Dual-form berberine for 24hr support* ✓ ✕ ✕ ✕ Added ALA for metabolic synergy* ✓ ✕ ✕ ✕ Maintains healthy insulin sensitivity* ✓ ✕ ✕ ? Supports healthy cholesterol levels* ✓ ✕ ✕ ? Gentle on digestion (low GI distress) ✓ ✓ ✓ ✕ Created by a thyroid expert ✓ ✕ ✕ ✕ Designed for use with thyroid meds ✓ ? ✓ ? Third-party tested for purity ✓ ? ✓ ? 60-day money back guarantee ✓ ? ✕ ? Common questions Frequently asked questions What changed in the new Berberine 500+? After extensive research and patient feedback, I’ve upgraded the Berberine 500+ formula to maximize its effectiveness for weight loss and blood sugar management. The new formula now contains dihydroberberine as GlucoVantage (a trademarked ingredient) in addition to berberine HCL. The combination of these two forms of berberine enhances their activity and prolongs their actions while minimizing negative side effects associated with berberine use. By removing ceylon cinnamon and chromium, we’ve created a more targeted formula with higher-quality, synergistic, and clinically-effective ingredients for those seeking the best possible results. Will Berberine 500+ help me lose weight? Yes, but perhaps a better way to state how it works is to say that it supports your existing weight loss efforts and makes those efforts more effective. Berberine 500+ will put your body into a state where weight loss is more effective and easier, but it is unlikely to cause weight loss without any other effort or input on your part. For this reason, you should always combine Berberine 500+ (or any of my other weight loss supplements) with things like a whole-food diet, regular exercise, and intermittent fasting. Using my weight loss supplements in this way will make your efforts far more effective and help you obtain your goals. What else should I be doing to help with weight loss? That is a great question! If you want to lose weight, keep it off, and change your body into a well-oiled fat-burning machine then you need to be doing more than just taking supplements. Yes, supplements can absolutely help, but they don’t replace important lifestyle changes like diet and exercise. No matter what you are doing, these need to be done as well. Based on my extensive research in helping patients with weight loss, here’s what works best when using Berberine 500+: A whole food diet (I’ve seen just about every single one work including the ketogenic diet, carnivore diet, low carb, vegan, whole30, etc. Just make sure to find a whole food diet that works for you). Regular exercise at least 3-5 times per week. My preference is weight lifting as it helps with weight loss and building muscle mass but pretty much anything can work here. If cycling is your thing then go for that. If you prefer pilates or yoga or something less intense, more power to you. What you do is less important than making sure you do it consistently. Intermittent fasting. If you are overweight then going for several hours to even a full day without food is incredibly helpful for balancing fat-storing hormones like leptin and insulin. My favorite fasting protocols include 2, 24-hour fasts each week, one meal a day, every other day fasting, or 16-hour fasting windows (see more information below). What fasting schedule works best when using your weight loss supplements? Fasting is simply going without food for a set period of time and it’s been a regular part of cultures and religions for thousands of years. Taking advantage of fasting as a therapy allows you to get more benefits out of weight loss therapies including supplements, medications, and even exercise. If you are new to fasting, here are several protocols that can be considered (I’ve seen them all work): 2, 24-hour fasts each week: This fasting protocol is easy, you just take 2 days out of the week and you go without food for a 24-hour period. Every other day fasting (3, 24-hour fasts each week): Every other day fasting is very similar but you can pick whatever 3 days work best for you based on your schedule. Most people who use this method do 1, 24 hour fast on Monday then again on Wednesday then again on Friday. OMAD (one meal a day): One meal a day is exactly as it sounds, you eat one gigantic meal each day. 16-hour fasting windows: This is similar to the one meal-a-day plan but it allows you to eat for an 8-hour window (as opposed to just one meal) every day. This means that each day you will be fasting for at least 16 hours. This is an easier way to jump into fasting if some of the other options seem too intense for you. Don’t be afraid to play around with these fasting protocols to find something that works best for your body and your situation! No matter what you do, just make sure you are doing some form of fasting if you are trying to lose weight! How do you take Berberine 500+? For best results take 2 capsules of berberine 500+ in the morning and 2 capsules in the evening with or without food. If you take thyroid medication take this supplement 30-60 minutes away from your thyroid medication. How long does it take to work? How quickly you see results depends on how you are checking for those results and factors including how resistant you are to weight loss. Most people, however, should expect to see changes after about 4-6 weeks of daily consistent use. This is because it takes time for the active ingredients to build up in your system and exert an impact on hormones (like insulin) and your muscle mass. Don’t be alarmed with this timing, though, because it’s perfectly normal for any therapy that actually helps you lose weight the right way to take about this long. If you are undergoing any weight loss therapy which purports to help you lose weight rapidly it will always come at a cost to your metabolic health. Safe and effective weight loss, on the other hand, allows you to lose weight and keep it off while also improving your overall health. Remember: You aren’t losing weight to get healthy, you are getting healthy to lose weight and this process takes time. How will I know if it’s working? When you are losing weight in a safe and